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Olanap 5mg Tablet 1 Strip
Olanap 5 is an atypical antipsychotic. It works by modulating levels of brain neurotransmitters—dopamine and serotonin—to help improve mood, behavior, and thought processes.
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✅ Description:
Olanap 5 is a prescription medication used to treat:
Schizophrenia – a mental condition characterized by hallucinations, delusions, and disorganized thinking.
Mania – episodes of abnormally elevated mood, energy, and activity, often seen in bipolar disorder.
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✔️ Dosage & Administration
- Can be taken with or without food, but it's ideal to take it at the same time daily to maintain stable drug levels.
- Do not chew or crush; swallow whole.
- If a dose is missed, take it as soon as it is remembered. Do not double dose.
- Do not discontinue abruptly without consulting your doctor—sudden stoppage may worsen symptoms.
Adult Dosing
Schizophrenia: Start with 5–10 mg/day. Titrate gradually if needed. Maintenance: 10–20 mg/day (max: 20 mg).
Bipolar Mania (Monotherapy or with lithium/valproate):
- Monotherapy: 10–15 mg/day initially.
- With lithium/valproate: 10 mg/day initially.
- Maintenance: 5–20 mg/day (max: 20 mg).
Bipolar Depression (with fluoxetine): Start at 5 mg/day, adjustable up to 20 mg/day in resistant cases.
Hepatic or Renal Impairment: Start at 5 mg/day.
Pediatric (13–17 yrs): Start with 2.5–5 mg/day; target dose: 10 mg/day; max: 20 mg/day.
Not recommended for children under 13.
✔️ Side Effects
Common (≥10%)
- Dizziness, drowsiness, weight gain
- Dry mouth, constipation
- Orthostatic hypotension (sudden BP drop when standing)
- Muscle stiffness, restlessness
- Tremor, increased prolactin
- Insomnia, elevated liver enzymes
Less Common (1–10%)
- Tremors, weakness, akathisia, parkinsonism
- Hypotension, postural hypotension
Rare but Serious (<1%)
- Sudden cardiac death, seizures, diabetic ketoacidosis
- Neuroleptic malignant syndrome (NMS)
- Pulmonary embolism, suicidal ideation, pancreatitis
- Tardive dyskinesia
Weight gain, blood sugar, and cholesterol elevation are notable metabolic concerns—lifestyle modification and regular monitoring are strongly advised.
✔️ Patient Guidance
- May cause sleepiness and dizziness—avoid driving until you know your response.
- Monitor weight, blood glucose, and cholesterol levels regularly.
- Do not smoke, as smoking may affect drug levels.
- Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.
- Stay hydrated and maintain a balanced diet and active lifestyle to minimize side effects.
✔️ Interaction
- May reduce the effectiveness of levodopa and dopamine agonists
- CYP1A2 inducers (e.g., rifampicin, omeprazole) increase clearance
- CYP1A2 inhibitors reduce clearance
- Carbamazepine increases metabolism
- Activated charcoal lowers oral absorption by 50–60%
- Use cautiously with alcohol and CNS depressants
✔️ Contraindications:
- Known allergy to Olanzapine
- Angle-closure glaucoma
- Use in breastfeeding is not recommended
- IM form contraindicated in patients with severe cardiovascular disease or recent heart surgery
✔️ Use with caution in patients with:
- Seizure disorders or risk of seizures
- Blood disorders, liver/kidney impairment
- Diabetes, Parkinson’s disease, prostatic enlargement
- Cardiovascular conditions, cerebrovascular disease
- Elderly patients with dementia-related psychosis
- Those exposed to medications prolonging QT interval or causing CNS depression
Patients should avoid driving or operating machinery until they understand how the drug affects them. Stand slowly from sitting/lying positions to avoid dizziness.
✔️ Storage:
Store below 30°C, away from light and moisture. Keep out of children’s reach.
Disclaimer:
ePharma sole intention is to ensure that its consumers get proper
information as musch as possible. Although we do not guarantee the
accuracy and the completeness of the information that provided and
here information is for informational purposes only.
The information contained herein should NOT be used as a substitute
for the advice of a qualified physician. This may not cover
everything about particular health conditions,
lab tests, medicines, all possible side effects, drug interactions,
warnings, alerts, etc. Please consult your healthcare professional
and discuss all your queries related to any disease or medicine. We
intend to support, not replace, the doctor-patient relationship.
